The Association between Impaired Language Production and Prefrontal Cortex Goal Maintenance Deficits in Medication-Naïve People with Schizophrenia

In the current study using functional magnetic resonance imaging, participants completed the Missing Letter task which has been found in previous research to involve goal maintenance demands (Cohen & Servan-Schreiber, 1992), to be associated with disorganized speech symptoms in people with schiz...

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Veröffentlicht in:NeuroImage (Orlando, Fla.) Fla.), 2009-07, Vol.47, p.S189-S189
Hauptverfasser: Becker, T.M., Cho, R.Y., Cohen, J.D., Kerns, J.G., Carter, C.S.
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Sprache:eng
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Zusammenfassung:In the current study using functional magnetic resonance imaging, participants completed the Missing Letter task which has been found in previous research to involve goal maintenance demands (Cohen & Servan-Schreiber, 1992), to be associated with disorganized speech symptoms in people with schizophrenia (Cohen, Barch, Carter, & Servan-Schreiber, 1999), and to involve activation of the prefrontal cortex (Kerns et al., 2004).
ISSN:1053-8119
1095-9572
DOI:10.1016/S1053-8119(09)72121-4