USING ASL METHOD FOR MONITORING OF BRAIN PERFUSION CHANGES IN RAT MODELS OF SCHIZOPHRENIA

USING ASL METHOD FOR MONITORING OF BRAIN PERFUSION CHANGES IN RAT MODELS OF SCHIZOPHRENIA

The MAM model was generated by acute intraperitoneal dose of MAM (22 mg/kg) to 10 pregnant Sprague-Dawley rat dams in the 17th day of their pregnancy. ASL was performed with a FAIR-RARE sequence with TR 10000 ms, TE 37.78 ms, image matrix 128x96, slice thickness 1.25 mm, 2D FOV 50.0x20.4 mm; from on...

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Veröffentlicht in:Physiological research 2016-07, Vol.65 (4), p.2P
Hauptverfasser: Drazanova, E, Grossova, L, Dvorakova, L, Pistovcakova, J, Ruda-Kucerova, J, Micale, V, Demlova, R, Kasparek, T, Starcuk, Z
Format: Artikel
Sprache:eng
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Animals
Dopamine
Rodents
Schizophrenia
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Zusammenfassung:The MAM model was generated by acute intraperitoneal dose of MAM (22 mg/kg) to 10 pregnant Sprague-Dawley rat dams in the 17th day of their pregnancy. ASL was performed with a FAIR-RARE sequence with TR 10000 ms, TE 37.78 ms, image matrix 128x96, slice thickness 1.25 mm, 2D FOV 50.0x20.4 mm; from one axial slice through the brain a set of 15 magnitude images with TI of 30, 50, 100, 200, 300, 500, 700, 900, 1000, 1100, 1500, 1800, 2200, 2800, 3200 ms was used to calculate the tissue blood flow map.
ISSN:0862-8408
1802-9973