The oral corticosteroid-sparing effect of omalizumab in children with severe asthma

Objective To report the oral corticosteroid-sparing effect of omalizumab in children with severe asthma. Design 16-week therapeutic trial. Setting Tertiary paediatric asthma clinic. Patients 34 children with severe asthma maintained on oral prednisolone (median age 12 years; 15 children

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Bibliographische Detailangaben
Veröffentlicht in:	Archives of disease in childhood 2012-07, Vol.97 (7), p.604-609
Hauptverfasser:	Brodlie, Malcolm, McKean, Michael C, Moss, Samantha, Spencer, David A
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adolescent Anti-Asthmatic Agents - adverse effects Anti-Asthmatic Agents - therapeutic use Antibodies, Anti-Idiotypic - adverse effects Antibodies, Anti-Idiotypic - therapeutic use Antibodies, Monoclonal, Humanized - adverse effects Antibodies, Monoclonal, Humanized - therapeutic use Asthma Asthma - drug therapy Asthma - physiopathology Asthma - rehabilitation Biological and medical sciences Body weight Care and treatment Career Choice Child Child, Preschool Children Control Drug Administration Schedule Educational Attainment Environmental Influences Forced Expiratory Volume - drug effects General aspects Glucocorticoids - administration & dosage Glucocorticoids - therapeutic use Health aspects Humans Injections, Subcutaneous Medical sciences Miscellaneous Omalizumab Pediatrics Prednisolone - administration & dosage Prevention and actions Psychometrics Public health. Hygiene Public health. Hygiene-occupational medicine Quality of Life Questionnaires Steroids Treatment Outcome
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Beschreibung
Zusammenfassung:	Objective To report the oral corticosteroid-sparing effect of omalizumab in children with severe asthma. Design 16-week therapeutic trial. Setting Tertiary paediatric asthma clinic. Patients 34 children with severe asthma maintained on oral prednisolone (median age 12 years; 15 children
ISSN:	0003-9888 1468-2044
DOI:	10.1136/archdischild-2011-301570