Novel approach to the design of potential bioactive alkaloid anabasine conjugates using click chemistry methodology
Anabasine‐containing azides and acetylenes were used as building blocks in copper(I)‐catalyzed 1,3‐dipolar cycloaddition reactions with a series of acetylenes and azides via click methodology to provide a range of anabasine conjugates being potential ligands for neuronal nicotinic acetylcholine rece...
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Veröffentlicht in: | Heteroatom chemistry 2016-09, Vol.27 (5), p.245-252 |
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container_title | Heteroatom chemistry |
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creator | Artyushin, Oleg I. Vinogradova, Natalya M. Sharova, Elena V. Genkina, Galina K. Brel, Valery K. |
description | Anabasine‐containing azides and acetylenes were used as building blocks in copper(I)‐catalyzed 1,3‐dipolar cycloaddition reactions with a series of acetylenes and azides via click methodology to provide a range of anabasine conjugates being potential ligands for neuronal nicotinic acetylcholine receptors. |
doi_str_mv | 10.1002/hc.21322 |
format | Article |
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title | Novel approach to the design of potential bioactive alkaloid anabasine conjugates using click chemistry methodology |
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