Synthesis, Spectral Characterization, and Antimicrobial Activity of Novel 2,4,6‐Trisubstituted Quinazoline Derivatives by Buchwald and Suzuki Coupling Reactions
A series of novel 2,4,6‐trisubstituted quinazoline derivatives were synthesized starting from 2‐amino‐5‐bromobenzoic acid. The structures of the newly synthesized compounds were established by IR, 1H NMR, 13C NMR, and mass spectral data. All the compounds were tested for antimicrobial activity....
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| Veröffentlicht in: | Journal of heterocyclic chemistry 2016-09, Vol.53 (5), p.1528-1533 |
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| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
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| Online-Zugang: | Volltext |
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| Zusammenfassung: | A series of novel 2,4,6‐trisubstituted quinazoline derivatives were synthesized starting from 2‐amino‐5‐bromobenzoic acid. The structures of the newly synthesized compounds were established by IR, 1H NMR, 13C NMR, and mass spectral data. All the compounds were tested for antimicrobial activity. |
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| ISSN: | 0022-152X 1943-5193 |
| DOI: | 10.1002/jhet.2459 |