Clinical usefulness of MMP-2 and TIMP-2 concentrations in the preoperative serum of patients with colorectal cancer

Clinical usefulness of MMP-2 and TIMP-2 concentrations in the preoperative serum of patients with colorectal cancer

Purpose: To evaluate the clinical significance of MMP-2 and TIMP-2 concentrations in the sera of patients diagnosed with colorectal cancer. Methods: The study group comprised 48 patients with colorectal carcinoma and 24 healthy controls. The serum concentration of MMP-2 and TIMP-2 proteins was evalu...

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Veröffentlicht in:Progress in health sciences 2016-06, Vol.6 (1), p.32-39
Hauptverfasser: Pryczynicz, Anna, Gryko, M, Dymicka-Piekarska, V, Lewczuk, L, Wakulewska, A, Kiszlo, P, Ozimkiewicz, M, Lebelt, A, Guzinska-Ustymowicz, K
Format: Artikel
Sprache:eng
Schlagworte:
Analysis
Cancer patients
Colorectal cancer
Health aspects
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Zusammenfassung:Purpose: To evaluate the clinical significance of MMP-2 and TIMP-2 concentrations in the sera of patients diagnosed with colorectal cancer. Methods: The study group comprised 48 patients with colorectal carcinoma and 24 healthy controls. The serum concentration of MMP-2 and TIMP-2 proteins was evaluated by the ELISA method. Results: The mean level of MMP-2 in the sera of patients with colorectal cancer was 39.4 ng/ml and was significantly lower compared with the control (p
ISSN:2083-1617
2083-6260
DOI:10.5604/01.3001.0009.5107