Vitamin D Toxicity; Stored and Released from Adipose Tissue?

Vitamin D Toxicity; Stored and Released from Adipose Tissue?

Vitamin D is a pro-hormone that plays an important role in body calcium regulation. Vitamin D toxicity occurs rarely due to its wide therapeutic index. A 38-year-old Iranian man was admitted to our hospital with a diagnosis of vitamin D toxicity. Laboratory test revealed hypercalcemia and elevated 2...

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Veröffentlicht in:Archives of Iranian medicine 2016-08, Vol.19 (8), p.597
Hauptverfasser: Ziaie, Hossein, Razmjou, Sara, Jomhouri, Rohollah, Jenabi, Arya
Format: Artikel
Sprache:eng
Schlagworte:
Adipose Tissue - chemistry
Adult
Body fat
Calcium - blood
Electrocardiography
Humans
Hypercalcemia - diagnosis
Iran
Male
Vitamin D - analogs & derivatives
Vitamin D - blood
Vitamin D - toxicity
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Zusammenfassung:Vitamin D is a pro-hormone that plays an important role in body calcium regulation. Vitamin D toxicity occurs rarely due to its wide therapeutic index. A 38-year-old Iranian man was admitted to our hospital with a diagnosis of vitamin D toxicity. Laboratory test revealed hypercalcemia and elevated 25-hydroxyvitamin D (25(OH)D) level. Despite the cessation of vitamin D intake and diuretic treatment, he presented four months later with high 25(OH)D level and similar clinical features. Due to the potential release of vitamin D from adipose tissue, serial monitoring of 25(OH)D level is recommended.
ISSN:1029-2977
1735-3947