ChemInform Abstract: Catalyst‐Free Three‐Component Tandem CDC Cyclization: Convenient Access to Isoindolinones from Aromatic Acid, Amides, and DMSO by a Pummerer‐Type Rearrangement
A catalyst free three‐component reaction of 3,4,5‐trimethoxybenzoic acid with sulfonamides or carboxylic amides and DMSO as methylene source proceeds through a Pummerer‐type rearrangement to provide a convenient access to N‐substituted isoindolinones.
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Veröffentlicht in: | ChemInform 2016-08, Vol.47 (36), p.no-no |
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creator | Wang, Peng‐Min Pu, Fan Liu, Ke‐Yan Li, Chao‐Jun Liu, Zhong‐Wen Shi, Xian‐Ying Fan, Juan Yang, Ming‐Yu Wei, Jun‐Fa |
description | A catalyst free three‐component reaction of 3,4,5‐trimethoxybenzoic acid with sulfonamides or carboxylic amides and DMSO as methylene source proceeds through a Pummerer‐type rearrangement to provide a convenient access to N‐substituted isoindolinones. |
doi_str_mv | 10.1002/chin.201636116 |
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subjects | indole derivatives, isoindole derivatives rearrangements ring closure reactions, annulation reactions |
title | ChemInform Abstract: Catalyst‐Free Three‐Component Tandem CDC Cyclization: Convenient Access to Isoindolinones from Aromatic Acid, Amides, and DMSO by a Pummerer‐Type Rearrangement |
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