ChemInform Abstract: Catalyst‐Free Three‐Component Tandem CDC Cyclization: Convenient Access to Isoindolinones from Aromatic Acid, Amides, and DMSO by a Pummerer‐Type Rearrangement

A catalyst free three‐component reaction of 3,4,5‐trimethoxybenzoic acid with sulfonamides or carboxylic amides and DMSO as methylene source proceeds through a Pummerer‐type rearrangement to provide a convenient access to N‐substituted isoindolinones.

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Veröffentlicht in:ChemInform 2016-08, Vol.47 (36), p.no-no
Hauptverfasser: Wang, Peng‐Min, Pu, Fan, Liu, Ke‐Yan, Li, Chao‐Jun, Liu, Zhong‐Wen, Shi, Xian‐Ying, Fan, Juan, Yang, Ming‐Yu, Wei, Jun‐Fa
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Sprache:eng
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Zusammenfassung:A catalyst free three‐component reaction of 3,4,5‐trimethoxybenzoic acid with sulfonamides or carboxylic amides and DMSO as methylene source proceeds through a Pummerer‐type rearrangement to provide a convenient access to N‐substituted isoindolinones.
ISSN:0931-7597
1522-2667
DOI:10.1002/chin.201636116