ChemInform Abstract: A Novel Synthesis of Disubstituted Quinazoline Diones with Differential N‐Substitution via a Copper‐Catalyzed Cross‐Coupling of Acyl Ureas

ChemInform Abstract: A Novel Synthesis of Disubstituted Quinazoline Diones with Differential N‐Substitution via a Copper‐Catalyzed Cross‐Coupling of Acyl Ureas

An intramolecular Buchwald—Hartwig‐type cross‐coupling furnishes the title compounds in good yields using CuI/hydroxyproline as catalyst/ligand system.

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Veröffentlicht in:ChemInform 2016-07, Vol.47 (33), p.no-no
Hauptverfasser: Durham, Emma, Perkins, Dave, Scott, James S., Wang, Jimmy, Watson, Sam
Format: Artikel
Sprache:eng
Schlagworte:
amination, N‐alkylation, N‐arylation
catalysis, phase‐transfer catalysis
fused pyrimidine derivatives
ring closure reactions, annulation reactions
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Zusammenfassung:An intramolecular Buchwald—Hartwig‐type cross‐coupling furnishes the title compounds in good yields using CuI/hydroxyproline as catalyst/ligand system.
ISSN:0931-7597
1522-2667
DOI:10.1002/chin.201633164