Stereoselective synthesis of tuberculostatic agent (S,S)-ethambutol
A simple and efficient asymmetric synthesis of (S,S)-Ethambutol has been carried out using a chiral butanediol. The synthesis was completed within six steps with an overall yield 53% and the enantiomeric purity of final product was 98%. All the reactions were very clean and the yields are excellent.
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| Veröffentlicht in: | Organic communications 2014-01, Vol.7 (1), p.28 |
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| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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