Rhodium-Catalyzed Cycloisomerization of 2-Alkynyl-N′-arylidenebenzohydrazides through exo-Carboamination

Rhodium-Catalyzed Cycloisomerization of 2-Alkynyl-N′-arylidenebenzohydrazides through exo-Carboamination

The rhodium‐catalyzed cycloisomerization reaction of 2‐alkynyl‐N′‐arylidenebenzohydrazides is reported. The reaction provides 4‐alkenylphthalazin‐1(2 H)‐ones through an intramolecular exo‐carboamination. Hook, line and sinker: 2‐Alkynyl‐N′‐arylidenebenzohydrazides underwent cycloisomerization via an...

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Veröffentlicht in:Asian journal of organic chemistry 2016-07, Vol.5 (7), p.891-894
Hauptverfasser: Matsuda, Takanori, Matsuda, Yoshiya
Format: Artikel
Sprache:eng
Schlagworte:
alkynes
carboamination
nitrogen heterocycles
Organic chemistry
phthalazinones
rhodium
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Zusammenfassung:The rhodium‐catalyzed cycloisomerization reaction of 2‐alkynyl‐N′‐arylidenebenzohydrazides is reported. The reaction provides 4‐alkenylphthalazin‐1(2 H)‐ones through an intramolecular exo‐carboamination. Hook, line and sinker: 2‐Alkynyl‐N′‐arylidenebenzohydrazides underwent cycloisomerization via an intramolecular exo‐carboamination to afford 4‐alkenylphthalazin‐1(2 H)‐ones in the presence of a catalytic amount of [RhCl(cod)]2 (cod=1,5‐cyclooctadiene).
ISSN:2193-5807
2193-5815
DOI:10.1002/ajoc.201600155