ChemInform Abstract: Exploiting the Multidentate Nature of Chiral Disulfonimides in a Multicomponent Reaction for the Asymmetric Synthesis of Pyrrolo[1,2‐a]indoles: A Remarkable Case of Enantioinversion

Chiral organocatalyst BDI is applied in the asymmetric 3‐component reaction between indol‐2‐carbaldehydes, anilines, and dihydrofuran giving the 2,3,3a,10a‐tetrahydro‐4H‐furo[3′,2′:4,5]pyrrolo[1,2‐a]indoles in modest to good yields and with modest to high enantioselectivities.

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	ChemInform 2016-06, Vol.47 (28), p.no-no
Hauptverfasser:	Galvan, Alicia, Gonzalez‐Perez, Adan B., Alvarez, Rosana, de Lera, Angel R., Fananas, Francisco J., Rodriguez, Felix
Format:	Artikel
Sprache:	eng
Schlagworte:	diastereoselective syntheses, enantioselective syntheses (incl. cis/trans‐isomerism) furan derivatives fused pyrrole derivatives multicomponent reactions organocatalysis ring closure reactions, annulation reactions
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Chiral organocatalyst BDI is applied in the asymmetric 3‐component reaction between indol‐2‐carbaldehydes, anilines, and dihydrofuran giving the 2,3,3a,10a‐tetrahydro‐4H‐furo[3′,2′:4,5]pyrrolo[1,2‐a]indoles in modest to good yields and with modest to high enantioselectivities.
ISSN:	0931-7597 1522-2667
DOI:	10.1002/chin.201628150