Utility of a single nasal polymerase chain reaction assay in predicting absence of skin and environmental contamination in hospitalized patients with past methicillin-resistant Staphylococcus

Utility of a single nasal polymerase chain reaction assay in predicting absence of skin and environmental contamination in hospitalized patients with past methicillin-resistant Staphylococcus

We evaluated hospitalized patients with a history of methicillin-resistant Staphylococcus aureus (MRSA) for persistent colonization and need for contact precautions. Up to 3 daily cultures of nares, skin, and any present wounds were compared with a single nasal polymerase chain reaction (PCR) assay....

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Veröffentlicht in:American journal of infection control 2016-06, Vol.44 (6), p.711
Hauptverfasser: Guerrero, Dubert M, Wagner, Matthew, Carson, Grace, Hanish, Christine, Thompson, Jody, Orr, Megan, Roth, Felix, Carson, Paul J
Format: Artikel
Sprache:eng
Schlagworte:
Contamination
Nosocomial infections
Polymerase chain reaction
Staphylococcus infections
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Zusammenfassung:We evaluated hospitalized patients with a history of methicillin-resistant Staphylococcus aureus (MRSA) for persistent colonization and need for contact precautions. Up to 3 daily cultures of nares, skin, and any present wounds were compared with a single nasal polymerase chain reaction (PCR) assay. Most patients (76.2%) were no longer colonized with MRSA. A single PCR assay was sufficient to exclude persistent colonization and environmental contamination and remove the contact precautions.
ISSN:0196-6553
1527-3296