Failure of primary atovaquone prophylaxis for prevention of toxoplasmosis in hematopoietic cell transplant recipients

Failure of primary atovaquone prophylaxis for prevention of toxoplasmosis in hematopoietic cell transplant recipients

The efficacy of primary prophylaxis with atovaquone in preventing Toxoplasma reactivation and disease in hematopoietic cell transplant (HCT) recipients is unknown. We describe 2 cases of atovaquone prophylaxis failure in pre‐HCT Toxoplasma‐seropositive (pre‐HCTSP) recipients who underwent allogeneic...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Transplant infectious disease 2016-06, Vol.18 (3), p.446-452
Hauptverfasser: Gajurel, K., Gomez, C.A., Dhakal, R., Vogel, H., Montoya, J.G.
Format: Artikel
Sprache:eng
Schlagworte:
atovaquone
hematopoietic cell transplant
preemptive treatment
Prophylaxis
Toxoplasma
Toxoplasmosis
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The efficacy of primary prophylaxis with atovaquone in preventing Toxoplasma reactivation and disease in hematopoietic cell transplant (HCT) recipients is unknown. We describe 2 cases of atovaquone prophylaxis failure in pre‐HCT Toxoplasma‐seropositive (pre‐HCTSP) recipients who underwent allogeneic HCT (allo‐HCT) and review the literature on atovaquone prophylaxis in HCT recipients.
ISSN:1398-2273
1399-3062
DOI:10.1111/tid.12532