ChemInform Abstract: Synthesis, Conformation and Antiproliferative Activity of Isothiazoloisoxazole 1,1‐Dioxides

Title compounds (III) are prepared by 1,3‐dipolar cycloaddition of nitriloxides, generated in situ, from hydroxymoyl chloride (II), to isoxazole 1,1‐dioxides (I).

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Bibliographische Detailangaben
Veröffentlicht in:	ChemInform 2016-06, Vol.47 (25), p.no-no
Hauptverfasser:	Blackburn, J., Molyneux, G., Pitard, A., Rice, C. R., Page, M. I., Afshinjavid, S., Javid, F. A., Coles, S. J., Horton, P. N., Hemming, K.
Format:	Artikel
Sprache:	eng
Schlagworte:	cycloaddition reactions diastereoselective syntheses, enantioselective syntheses (incl. cis/trans‐isomerism) isoxazole derivatives structure (organic substances) thiazole derivatives
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Beschreibung
Zusammenfassung:	Title compounds (III) are prepared by 1,3‐dipolar cycloaddition of nitriloxides, generated in situ, from hydroxymoyl chloride (II), to isoxazole 1,1‐dioxides (I).
ISSN:	0931-7597 1522-2667
DOI:	10.1002/chin.201625140