A Sulphasalazine-Induced Hypersensitivity Syndrome Mimicking Viral Rash Illness

The etiology of fever and rash is a challenging condition for clinicians in the diagnosis. Viral and bacterial agents are the most etiological factors, but drugs, chemicals, foods, and rheumatic diseases can also cause fever and rash. Drug-induced hypersensitivity syndrome is one of the life-threatening reactions in which systemic multiple organ involvement can be seen. The mortality rate in drug-induced hypersensitivity syndrome (DIHS) is about 20%. Therefore, it is important to clarify the etiology without delay. In our study, we aimed to present a rare case of salazopyrin hypersensitivity mimicking a viral illness with skin rash. (The Me­di­cal Bul­le­tin of Ha­se­ki 2015; 53: 277-80)