P90 Osteoporosis in Non-Cystic Fibrosis Bronchiectasis (NCFBr) Adults

Introduction Whilst osteoporosis is associated with COPD, little is known on its prevalence in non-cystic fibrosis bronchiectasis (NCFBr). We assessed the impact of factors associated with NCFBr disease severity on bone mineral density (BMD) and DEXA referral patterns in NCFBr. Methods BMD reports from DEXA scanners were collected for all NCFBr patients from our specialist clinic database and T-scores for lumbar spine (LS), total left hip (TLH) and neck of femur (NOF) were recorded. Osteoporosis was defined as T-scores ≤–2.5, osteopenia between –1 and –2.5 and normal BMD ≥–1. FEV1 values, exacerbation frequency and Pseudomonas aeruginosa chronic infection (defined as >1 positive sputum result in past 12 months) were recorded. Results 336 NCFBr patients were identified attending the specialist clinic. 101 patients had DEXA scans performed (30%); 96 reports were retrievable. The male:female ratio was significantly different between scanned patients (29%:71%) and the entire NCFBr patient cohort (41%:59%): p