Two cases of birth defects overlapping Stratton-Parker syndrome after multiple pesticide exposure
Sex Male Male Male Age at last examination 17 months 5 years 1 month 1 year 1 month Early developmental delay + + + Congenital heart defects + + - Pituitary gland hypoplasia NR + NR Wormian bones + NR NR Renal hypoplasia + NR NR Bowel defects Imperforate anus Imperforate anus Imperforate anus Genita...
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| Veröffentlicht in: | Occupational and environmental medicine (London, England) England), 2010-05, Vol.67 (5), p.359-359 |
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| creator | Mesnage, R Clair, E Spiroux de Vendômois, J Séralini, G-E |
| description | Sex Male Male Male Age at last examination 17 months 5 years 1 month 1 year 1 month Early developmental delay + + + Congenital heart defects + + - Pituitary gland hypoplasia NR + NR Wormian bones + NR NR Renal hypoplasia + NR NR Bowel defects Imperforate anus Imperforate anus Imperforate anus Genital abnormalities Bilateral cryptorchidism, hypospadias - Micropenis, hypospadias Brachycamptodactyly + NR NR Hypoplastic nose + + + +, present; -, absent; NR, not reported. The adverse effects of these pesticide cocktails are more than the sum of the effects of their separate constituents. [...]in our case we cannot exclude the role of a cocktail of endocrine disruptors at epigenetic, genetic or physiological levels during parental gametogenesis or pregnancy. |
| doi_str_mv | 10.1136/oem.2009.052969 |
| format | Article |
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The adverse effects of these pesticide cocktails are more than the sum of the effects of their separate constituents. [...]in our case we cannot exclude the role of a cocktail of endocrine disruptors at epigenetic, genetic or physiological levels during parental gametogenesis or pregnancy.</description><identifier>ISSN: 1351-0711</identifier><identifier>EISSN: 1470-7926</identifier><identifier>DOI: 10.1136/oem.2009.052969</identifier><identifier>PMID: 19951932</identifier><language>eng</language><publisher>England: BMJ Publishing Group Ltd</publisher><subject>Abnormalities, Drug-Induced - etiology ; Abnormalities, Multiple - chemically induced ; Birth defects ; Child, Preschool ; congenital anomalies ; Congenital diseases ; Defects ; endocrine disorders ; Endocrine disruptors ; environmental pollution ; Epidemiology ; Fathers ; Female ; France - epidemiology ; Genitalia ; Growth hormones ; Humans ; Hypospadias ; Imperforate anus ; Infant ; LETTER ; Male ; Maternal Exposure - adverse effects ; Paternal Exposure - adverse effects ; Pesticides ; Pesticides - toxicity ; pollution ; Pregnancy ; Prenatal Exposure Delayed Effects - chemically induced ; Stratton-Parker syndrome ; Toxicology</subject><ispartof>Occupational and environmental medicine (London, England), 2010-05, Vol.67 (5), p.359-359</ispartof><rights>2010, Published by the BMJ Publishing Group Limited For permission to use, (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.</rights><rights>Copyright © 2010 BMJ Publishing Group</rights><rights>Copyright: 2010 (c) 2010, Published by the BMJ Publishing Group Limited For permission to use, (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://oem.bmj.com/content/67/5/359.full.pdf$$EPDF$$P50$$Gbmj$$H</linktopdf><linktohtml>$$Uhttps://oem.bmj.com/content/67/5/359.full$$EHTML$$P50$$Gbmj$$H</linktohtml><link.rule.ids>114,115,314,776,780,799,23552,27903,27904,57995,58228,77346,77377</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19951932$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mesnage, R</creatorcontrib><creatorcontrib>Clair, E</creatorcontrib><creatorcontrib>Spiroux de Vendômois, J</creatorcontrib><creatorcontrib>Séralini, G-E</creatorcontrib><title>Two cases of birth defects overlapping Stratton-Parker syndrome after multiple pesticide exposure</title><title>Occupational and environmental medicine (London, England)</title><addtitle>Occup Environ Med</addtitle><description>Sex Male Male Male Age at last examination 17 months 5 years 1 month 1 year 1 month Early developmental delay + + + Congenital heart defects + + - Pituitary gland hypoplasia NR + NR Wormian bones + NR NR Renal hypoplasia + NR NR Bowel defects Imperforate anus Imperforate anus Imperforate anus Genital abnormalities Bilateral cryptorchidism, hypospadias - Micropenis, hypospadias Brachycamptodactyly + NR NR Hypoplastic nose + + + +, present; -, absent; NR, not reported. The adverse effects of these pesticide cocktails are more than the sum of the effects of their separate constituents. [...]in our case we cannot exclude the role of a cocktail of endocrine disruptors at epigenetic, genetic or physiological levels during parental gametogenesis or pregnancy.</description><subject>Abnormalities, Drug-Induced - etiology</subject><subject>Abnormalities, Multiple - chemically induced</subject><subject>Birth defects</subject><subject>Child, Preschool</subject><subject>congenital anomalies</subject><subject>Congenital diseases</subject><subject>Defects</subject><subject>endocrine disorders</subject><subject>Endocrine disruptors</subject><subject>environmental pollution</subject><subject>Epidemiology</subject><subject>Fathers</subject><subject>Female</subject><subject>France - epidemiology</subject><subject>Genitalia</subject><subject>Growth hormones</subject><subject>Humans</subject><subject>Hypospadias</subject><subject>Imperforate anus</subject><subject>Infant</subject><subject>LETTER</subject><subject>Male</subject><subject>Maternal Exposure - adverse effects</subject><subject>Paternal Exposure - adverse effects</subject><subject>Pesticides</subject><subject>Pesticides - toxicity</subject><subject>pollution</subject><subject>Pregnancy</subject><subject>Prenatal Exposure Delayed Effects - chemically induced</subject><subject>Stratton-Parker syndrome</subject><subject>Toxicology</subject><issn>1351-0711</issn><issn>1470-7926</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNpFkU1PGzEQhi3UCkLKmROVpd6QNnjs3Tg-VmkJIKCVCoib5a-FTbPx1vYW-Pc4Wgin-XgfzYzmRegQyASATU-8ayeUEDEhFRVTsYNGUHJScEGnn3LOKigIB9hD-zEuCQHGGd1FeyBEBYLREVI3Tx4bFV3Evsa6CekRW1c7k3Ljvwsr1XXN-gH_SUGl5NfFbxX-uoDjy9oG3zqs6pTLtl-lpls53LmYGtNYh91z52Mf3Bf0uVar6A7e4hjdnv68mZ8Vl78W5_Pvl4VmBFJhdKX1TBiiLFhKLbElr7UWpaVmppUG0FVtmLGiNIZZZlVdzpwmlQJluKjZGH0b5nbB_-vzGXLp-7DOKyXwGTBSlYJm6usb1evWWdmFplXhRb5_JANHA7CMyYetTjkXnHPIejHoTUzueavnr8gpZ7yS13dz-WMxv7-6uijlIvPHA6_b5cc2Ijf2yWyf3NgnB_vYK5oki8s</recordid><startdate>201005</startdate><enddate>201005</enddate><creator>Mesnage, R</creator><creator>Clair, E</creator><creator>Spiroux de Vendômois, J</creator><creator>Séralini, G-E</creator><general>BMJ Publishing Group Ltd</general><general>BMJ Publishing Group</general><general>BMJ Publishing Group LTD</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8C1</scope><scope>8FE</scope><scope>8FG</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>L6V</scope><scope>M0S</scope><scope>M1P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>PATMY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PTHSS</scope><scope>PYCSY</scope></search><sort><creationdate>201005</creationdate><title>Two cases of birth defects overlapping Stratton-Parker syndrome after multiple pesticide exposure</title><author>Mesnage, R ; Clair, E ; Spiroux de Vendômois, J ; Séralini, G-E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b301t-cb5bb89c0ad1d22d0d47fbb94d2c8bab11b5fc3cd94cc3d3daf48eb05a1ac79f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Abnormalities, Drug-Induced - etiology</topic><topic>Abnormalities, Multiple - chemically induced</topic><topic>Birth defects</topic><topic>Child, Preschool</topic><topic>congenital anomalies</topic><topic>Congenital diseases</topic><topic>Defects</topic><topic>endocrine disorders</topic><topic>Endocrine disruptors</topic><topic>environmental pollution</topic><topic>Epidemiology</topic><topic>Fathers</topic><topic>Female</topic><topic>France - epidemiology</topic><topic>Genitalia</topic><topic>Growth hormones</topic><topic>Humans</topic><topic>Hypospadias</topic><topic>Imperforate anus</topic><topic>Infant</topic><topic>LETTER</topic><topic>Male</topic><topic>Maternal Exposure - adverse effects</topic><topic>Paternal Exposure - adverse effects</topic><topic>Pesticides</topic><topic>Pesticides - toxicity</topic><topic>pollution</topic><topic>Pregnancy</topic><topic>Prenatal Exposure Delayed Effects - chemically induced</topic><topic>Stratton-Parker syndrome</topic><topic>Toxicology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mesnage, R</creatorcontrib><creatorcontrib>Clair, E</creatorcontrib><creatorcontrib>Spiroux de Vendômois, J</creatorcontrib><creatorcontrib>Séralini, G-E</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Engineering Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Engineering Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Environmental Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Engineering Collection</collection><collection>Environmental Science Collection</collection><jtitle>Occupational and environmental medicine (London, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mesnage, R</au><au>Clair, E</au><au>Spiroux de Vendômois, J</au><au>Séralini, G-E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Two cases of birth defects overlapping Stratton-Parker syndrome after multiple pesticide exposure</atitle><jtitle>Occupational and environmental medicine (London, England)</jtitle><addtitle>Occup Environ Med</addtitle><date>2010-05</date><risdate>2010</risdate><volume>67</volume><issue>5</issue><spage>359</spage><epage>359</epage><pages>359-359</pages><issn>1351-0711</issn><eissn>1470-7926</eissn><abstract>Sex Male Male Male Age at last examination 17 months 5 years 1 month 1 year 1 month Early developmental delay + + + Congenital heart defects + + - Pituitary gland hypoplasia NR + NR Wormian bones + NR NR Renal hypoplasia + NR NR Bowel defects Imperforate anus Imperforate anus Imperforate anus Genital abnormalities Bilateral cryptorchidism, hypospadias - Micropenis, hypospadias Brachycamptodactyly + NR NR Hypoplastic nose + + + +, present; -, absent; NR, not reported. The adverse effects of these pesticide cocktails are more than the sum of the effects of their separate constituents. [...]in our case we cannot exclude the role of a cocktail of endocrine disruptors at epigenetic, genetic or physiological levels during parental gametogenesis or pregnancy.</abstract><cop>England</cop><pub>BMJ Publishing Group Ltd</pub><pmid>19951932</pmid><doi>10.1136/oem.2009.052969</doi><tpages>1</tpages></addata></record> |
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| ispartof | Occupational and environmental medicine (London, England), 2010-05, Vol.67 (5), p.359-359 |
| issn | 1351-0711 1470-7926 |
| language | eng |
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| source | Jstor Complete Legacy; MEDLINE; BMJ Journals - NESLi2 |
| subjects | Abnormalities, Drug-Induced - etiology Abnormalities, Multiple - chemically induced Birth defects Child, Preschool congenital anomalies Congenital diseases Defects endocrine disorders Endocrine disruptors environmental pollution Epidemiology Fathers Female France - epidemiology Genitalia Growth hormones Humans Hypospadias Imperforate anus Infant LETTER Male Maternal Exposure - adverse effects Paternal Exposure - adverse effects Pesticides Pesticides - toxicity pollution Pregnancy Prenatal Exposure Delayed Effects - chemically induced Stratton-Parker syndrome Toxicology |
| title | Two cases of birth defects overlapping Stratton-Parker syndrome after multiple pesticide exposure |
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