Phaeochromocytoma and thrombotic microangiopathy: favourable outcome despite advanced renal failure
An MRI scan of the abdomen was performed for diffuse abdominal pain and showed a 4 cm tumour in the left adrenal gland ( figure 1A ). [...]a working diagnosis of phaeochromocytoma with malignant hypertension and thrombotic microangiopathy was made, and immunosuppressive therapy was discontinued. Bec...
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Veröffentlicht in: | Journal of clinical pathology 2010-08, Vol.63 (8), p.754-756 |
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creator | Schweizer, Heiko Boehm, Joachim Winterer, Jan Thorsten Wild, Damian Neumann, Hartmut P H Wiech, Thorsten Stubanus, Mike Kuehn, E Wolfgang |
description | An MRI scan of the abdomen was performed for diffuse abdominal pain and showed a 4 cm tumour in the left adrenal gland ( figure 1A ). [...]a working diagnosis of phaeochromocytoma with malignant hypertension and thrombotic microangiopathy was made, and immunosuppressive therapy was discontinued. Because of the clinical response to plasmaphaeresis, we think that phaeochromocytoma complicated by malignant hypertension coexisting with TTP is a likely diagnosis in this case. |
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[...]a working diagnosis of phaeochromocytoma with malignant hypertension and thrombotic microangiopathy was made, and immunosuppressive therapy was discontinued. Because of the clinical response to plasmaphaeresis, we think that phaeochromocytoma complicated by malignant hypertension coexisting with TTP is a likely diagnosis in this case.</description><identifier>ISSN: 0021-9746</identifier><identifier>EISSN: 1472-4146</identifier><identifier>DOI: 10.1136/jcp.2010.077511</identifier><identifier>PMID: 20702482</identifier><identifier>CODEN: JCPAAK</identifier><language>eng</language><publisher>London: BMJ Publishing Group Ltd and Association of Clinical Pathologists</publisher><subject>Abdomen ; Acute Kidney Injury - etiology ; Adrenal gland ; Adrenal Gland Neoplasms - complications ; Adrenals. Adrenal axis. Renin-angiotensin system (diseases) ; Adult ; arteries ; Biological and medical sciences ; Biopsy ; blood vessels ; Dehydrogenases ; Endocrinopathies ; Family medical history ; Female ; Gangrene ; Humans ; Hypertension ; Investigative techniques, diagnostic techniques (general aspects) ; kidney ; Magnetic Resonance Imaging ; Medical sciences ; nephrology ; Nephrology. Urinary tract diseases ; Nephropathies. Renovascular diseases. Renal failure ; Non tumoral diseases. Target tissue resistance. Benign neoplasms ; Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques ; Pheochromocytoma - complications ; Plasma ; Prognosis ; Renal failure ; Thrombotic Microangiopathies - etiology ; Tumors ; Urine</subject><ispartof>Journal of clinical pathology, 2010-08, Vol.63 (8), p.754-756</ispartof><rights>2010, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.</rights><rights>2015 INIST-CNRS</rights><rights>Copyright: 2010 (c) 2010, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b395t-e049b9d96d2bae4f38cabfb6ea99f04e052156a1abb761985166371a516adc4a3</citedby><cites>FETCH-LOGICAL-b395t-e049b9d96d2bae4f38cabfb6ea99f04e052156a1abb761985166371a516adc4a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://jcp.bmj.com/content/63/8/754.full.pdf$$EPDF$$P50$$Gbmj$$H</linktopdf><linktohtml>$$Uhttps://jcp.bmj.com/content/63/8/754.full$$EHTML$$P50$$Gbmj$$H</linktohtml><link.rule.ids>114,115,314,776,780,3183,23550,27901,27902,77342,77373</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23092224$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20702482$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Schweizer, Heiko</creatorcontrib><creatorcontrib>Boehm, Joachim</creatorcontrib><creatorcontrib>Winterer, Jan Thorsten</creatorcontrib><creatorcontrib>Wild, Damian</creatorcontrib><creatorcontrib>Neumann, Hartmut P H</creatorcontrib><creatorcontrib>Wiech, Thorsten</creatorcontrib><creatorcontrib>Stubanus, Mike</creatorcontrib><creatorcontrib>Kuehn, E Wolfgang</creatorcontrib><title>Phaeochromocytoma and thrombotic microangiopathy: favourable outcome despite advanced renal failure</title><title>Journal of clinical pathology</title><addtitle>J Clin Pathol</addtitle><description>An MRI scan of the abdomen was performed for diffuse abdominal pain and showed a 4 cm tumour in the left adrenal gland ( figure 1A ). [...]a working diagnosis of phaeochromocytoma with malignant hypertension and thrombotic microangiopathy was made, and immunosuppressive therapy was discontinued. Because of the clinical response to plasmaphaeresis, we think that phaeochromocytoma complicated by malignant hypertension coexisting with TTP is a likely diagnosis in this case.</description><subject>Abdomen</subject><subject>Acute Kidney Injury - etiology</subject><subject>Adrenal gland</subject><subject>Adrenal Gland Neoplasms - complications</subject><subject>Adrenals. Adrenal axis. Renin-angiotensin system (diseases)</subject><subject>Adult</subject><subject>arteries</subject><subject>Biological and medical sciences</subject><subject>Biopsy</subject><subject>blood vessels</subject><subject>Dehydrogenases</subject><subject>Endocrinopathies</subject><subject>Family medical history</subject><subject>Female</subject><subject>Gangrene</subject><subject>Humans</subject><subject>Hypertension</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>kidney</subject><subject>Magnetic Resonance Imaging</subject><subject>Medical sciences</subject><subject>nephrology</subject><subject>Nephrology. Urinary tract diseases</subject><subject>Nephropathies. Renovascular diseases. Renal failure</subject><subject>Non tumoral diseases. Target tissue resistance. Benign neoplasms</subject><subject>Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques</subject><subject>Pheochromocytoma - complications</subject><subject>Plasma</subject><subject>Prognosis</subject><subject>Renal failure</subject><subject>Thrombotic Microangiopathies - etiology</subject><subject>Tumors</subject><subject>Urine</subject><issn>0021-9746</issn><issn>1472-4146</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqFkE1v1DAQhi1URLeFMzcUqeJSKa2_Yse9wapbkCrgAAj1Yo0dh802WQfbqbr_vl5lKUdOI4-fGb3zIPSW4AtCmLjc2PGC4vzCUlaEvEALwiUtOeHiCC0wpqRUkotjdBLjBmPCJGGv0DHFElNe0wWy39bgvF0HP3i7S36AArZNkfYN41Nni6GzwcP2d-dHSOvdVdHCg58CmN4VfkrWD65oXBy75ApoHmBrXVMEt4U-k10_BfcavWyhj-7NoZ6iH6vr78tP5e3Xm8_LD7elYapKpcNcGdUo0VADjrestmBaIxwo1WLucEVJJYCAMVIQVVdEiHwP5AqN5cBO0dm8dwz-z-Ri0pscNAeJmsiaYCZwLTN1OVP5rBiDa_UYugHCThOs91J1lqr3UvUsNU-8O-ydzOCaZ_6vxQy8PwAQLfRtyBK6-I9jWFFKeebKmetico_P_xDutZBMVvrLz6X-uKJ34tfdUq8yfz7zZtj8N-UT_pudRg</recordid><startdate>20100801</startdate><enddate>20100801</enddate><creator>Schweizer, Heiko</creator><creator>Boehm, Joachim</creator><creator>Winterer, Jan Thorsten</creator><creator>Wild, Damian</creator><creator>Neumann, Hartmut P H</creator><creator>Wiech, Thorsten</creator><creator>Stubanus, Mike</creator><creator>Kuehn, E Wolfgang</creator><general>BMJ Publishing Group Ltd and Association of Clinical Pathologists</general><general>BMJ Publishing Group</general><general>BMJ Publishing Group LTD</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope></search><sort><creationdate>20100801</creationdate><title>Phaeochromocytoma and thrombotic microangiopathy: favourable outcome despite advanced renal failure</title><author>Schweizer, Heiko ; Boehm, Joachim ; Winterer, Jan Thorsten ; Wild, Damian ; Neumann, Hartmut P H ; Wiech, Thorsten ; Stubanus, Mike ; Kuehn, E Wolfgang</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b395t-e049b9d96d2bae4f38cabfb6ea99f04e052156a1abb761985166371a516adc4a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Abdomen</topic><topic>Acute Kidney Injury - etiology</topic><topic>Adrenal gland</topic><topic>Adrenal Gland Neoplasms - complications</topic><topic>Adrenals. Adrenal axis. Renin-angiotensin system (diseases)</topic><topic>Adult</topic><topic>arteries</topic><topic>Biological and medical sciences</topic><topic>Biopsy</topic><topic>blood vessels</topic><topic>Dehydrogenases</topic><topic>Endocrinopathies</topic><topic>Family medical history</topic><topic>Female</topic><topic>Gangrene</topic><topic>Humans</topic><topic>Hypertension</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>kidney</topic><topic>Magnetic Resonance Imaging</topic><topic>Medical sciences</topic><topic>nephrology</topic><topic>Nephrology. Urinary tract diseases</topic><topic>Nephropathies. Renovascular diseases. Renal failure</topic><topic>Non tumoral diseases. Target tissue resistance. Benign neoplasms</topic><topic>Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques</topic><topic>Pheochromocytoma - complications</topic><topic>Plasma</topic><topic>Prognosis</topic><topic>Renal failure</topic><topic>Thrombotic Microangiopathies - etiology</topic><topic>Tumors</topic><topic>Urine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Schweizer, Heiko</creatorcontrib><creatorcontrib>Boehm, Joachim</creatorcontrib><creatorcontrib>Winterer, Jan Thorsten</creatorcontrib><creatorcontrib>Wild, Damian</creatorcontrib><creatorcontrib>Neumann, Hartmut P H</creatorcontrib><creatorcontrib>Wiech, Thorsten</creatorcontrib><creatorcontrib>Stubanus, Mike</creatorcontrib><creatorcontrib>Kuehn, E Wolfgang</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><jtitle>Journal of clinical pathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Schweizer, Heiko</au><au>Boehm, Joachim</au><au>Winterer, Jan Thorsten</au><au>Wild, Damian</au><au>Neumann, Hartmut P H</au><au>Wiech, Thorsten</au><au>Stubanus, Mike</au><au>Kuehn, E Wolfgang</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Phaeochromocytoma and thrombotic microangiopathy: favourable outcome despite advanced renal failure</atitle><jtitle>Journal of clinical pathology</jtitle><addtitle>J Clin Pathol</addtitle><date>2010-08-01</date><risdate>2010</risdate><volume>63</volume><issue>8</issue><spage>754</spage><epage>756</epage><pages>754-756</pages><issn>0021-9746</issn><eissn>1472-4146</eissn><coden>JCPAAK</coden><abstract>An MRI scan of the abdomen was performed for diffuse abdominal pain and showed a 4 cm tumour in the left adrenal gland ( figure 1A ). [...]a working diagnosis of phaeochromocytoma with malignant hypertension and thrombotic microangiopathy was made, and immunosuppressive therapy was discontinued. Because of the clinical response to plasmaphaeresis, we think that phaeochromocytoma complicated by malignant hypertension coexisting with TTP is a likely diagnosis in this case.</abstract><cop>London</cop><pub>BMJ Publishing Group Ltd and Association of Clinical Pathologists</pub><pmid>20702482</pmid><doi>10.1136/jcp.2010.077511</doi><tpages>3</tpages></addata></record> |
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subjects | Abdomen Acute Kidney Injury - etiology Adrenal gland Adrenal Gland Neoplasms - complications Adrenals. Adrenal axis. Renin-angiotensin system (diseases) Adult arteries Biological and medical sciences Biopsy blood vessels Dehydrogenases Endocrinopathies Family medical history Female Gangrene Humans Hypertension Investigative techniques, diagnostic techniques (general aspects) kidney Magnetic Resonance Imaging Medical sciences nephrology Nephrology. Urinary tract diseases Nephropathies. Renovascular diseases. Renal failure Non tumoral diseases. Target tissue resistance. Benign neoplasms Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Pheochromocytoma - complications Plasma Prognosis Renal failure Thrombotic Microangiopathies - etiology Tumors Urine |
title | Phaeochromocytoma and thrombotic microangiopathy: favourable outcome despite advanced renal failure |
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