e0699 Late gadolinium-enhanced cardiac MRI in restrictive cardiomyopathy

Objective To evaluate the diagnostic value of MRI in combination of late gadolinium-enhanced imaging in the identification of restrictive cardiomyopathy (RCM). Methods 116 patients with RCM underwent ECG, X-ray, Echocardiography and MRI. The final diagnosis was made on comprehensive evaluation in consideration of patients’ history, clinical symptom and sign, imaging modalities. All patients had objective evidence of impaired cardiac filling and were referred to rule out pericardial thickening. Five histologically proven cases with RCM included heart transplantation in four patients with RCM, endomyocardial biopsy in one patient with RCM. 55 normal subjects were used for reference. All patients were divided into two groups according to contrast-enhanced MRI: RCM with delayed enhancement (RCM with DE, n=35) and RCM without delayed enhancement (RCM without DE, n=81). Quantitative measurement of bi-atrial and bi-ventricular size, ventricular septal and left free wall thickness were done. A paired t-test was used for statistic analysis and a p value of less than 0.05 was considered significant. Qualitative assessment of segmental wall motion, in this present study. Results The parameters, such as bi-atrial size, right ventricular diastolic diameter, ventricular septal and left free wall thickness were significantly larger in 116 patients with RCM than in normal subjects (p