LONGITUDINAL ASSOCIATION OF SERUM HOMOCYSTEINE LEVELS WITH ALL-CAUSE MORTALITY IN ADULTS WITH HYPERTENSION: IMPACT OF FOLIC-ACID INTERVENTION AND MTHFR C677T GENE POLYMORPHISM

LONGITUDINAL ASSOCIATION OF SERUM HOMOCYSTEINE LEVELS WITH ALL-CAUSE MORTALITY IN ADULTS WITH HYPERTENSION: IMPACT OF FOLIC-ACID INTERVENTION AND MTHFR C677T GENE POLYMORPHISM

[...]data are limited on the association of Hcy with all-cause mortality in low folate regions, and uncertainty remains about whether folic acid therapy can reduce the risk of all-cause mortality associated with HHcy and whether the effect varies by MTHFR (a key enzyme involved in Hcy metabolism) ge...

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Veröffentlicht in:Journal of the American College of Cardiology 2016-04, Vol.67 (13), p.1911-1911
Hauptverfasser: Xu, Benjamin, Kong, Xiangyi, Xu, Richard, Min, Zhao, Zhang, Chunyan, Yu, Tao, Liu, Lishun, Fan, Fangfang, Zhang, Yan, Huang, Xiao, Cheng, Xiaoshu, Qin, Xianhui, Wang, Binyan, Gu, Jin, Li, Xiangyi, Chen, Yundai, Yang, Tianlun, Sun, Ningling, Zhao, Lianyou, Hou, Fan Fan, Ge, Junbo, Dong, Qiang, Sun, Yingxian, Huo, Yong, Jianping, Li
Format: Artikel
Sprache:eng
Schlagworte:
Acids
Cardiology
Cardiovascular
Health risk assessment
Heart attacks
Homocysteine
Internal Medicine
Mortality
Survival analysis
Vitamin B
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Zusammenfassung:[...]data are limited on the association of Hcy with all-cause mortality in low folate regions, and uncertainty remains about whether folic acid therapy can reduce the risk of all-cause mortality associated with HHcy and whether the effect varies by MTHFR (a key enzyme involved in Hcy metabolism) gene C677T polymorphism.
ISSN:0735-1097
1558-3597
DOI:10.1016/S0735-1097(16)31912-X