Unusual case of scrapie in a ewe

Histological screening of the formalin-fixed medulla found marked neuropil and neuronal vacuolation consistent with scrapie, which was subsequently confirmed using immunohistochemistry to demonstrate pathological accumulation of PrP Sc . Scrapie, a chronic fatal disease of adult sheep and goats, is...

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Veröffentlicht in:Veterinary record 2005-10, Vol.157 (16), p.492-492
Hauptverfasser: Wessels, M. E., Higgins, R. J., Gresham, A. C. J., Tymms, D. P.
Format: Artikel
Sprache:eng
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Zusammenfassung:Histological screening of the formalin-fixed medulla found marked neuropil and neuronal vacuolation consistent with scrapie, which was subsequently confirmed using immunohistochemistry to demonstrate pathological accumulation of PrP Sc . Scrapie, a chronic fatal disease of adult sheep and goats, is the prototypic disease of the group of transmissible spongiform encephalopathies and is notifiable throughout the EU .
ISSN:0042-4900
2042-7670
DOI:10.1136/vr.157.16.492