AB0807 Nailfold capillaroscopy findings are related to the pulmonary function tests values in patients with systemic sclerosis

Objectives To determine the relation between different pathological capillaroscopic findings and pulmonary function tests in patients with scleroderma. Methods Retrospective observational study of a cohort of patients with systemic sclerosis (SSc) or early SSc (eSSc) followed in Rheumatology Unit of...

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Veröffentlicht in:Annals of the rheumatic diseases 2013-06, Vol.71 (Suppl 3), p.684
Hauptverfasser: Castellví, I., Sarmiento, M., Corica, M.E., Moya-Alvarado, P., Diaz-Torne, C., Geli, C., Laiz, A., Rodriguez de la Serna, A., Diaz-Lopez, C., de Llobet, J.M., Casademont, J.
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Sprache:eng
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Zusammenfassung:Objectives To determine the relation between different pathological capillaroscopic findings and pulmonary function tests in patients with scleroderma. Methods Retrospective observational study of a cohort of patients with systemic sclerosis (SSc) or early SSc (eSSc) followed in Rheumatology Unit of a University Hospital from 1975 to 2011. Patients who had a nailfold videocapillaroscopy with 120x magnification were selected. The following pathological findings were considered: presence of megacapillaries and/or angiogenesis and loss of capillary density. Capillaroscopic findings were compared with the following values of lung function tests performed in the same year of the capillaroscopy: % predicted forced vital capacity (FVC), DLCO and the FVC/DLCO ratio. The following variables were also included: sex, type of SSc, presence of digital ulcers, interstitial lung disease (ILD), scleroderma renal crisis (SRC) and pulmonary hypertension determined by echocardiogram. Statistical analysis was performed by T Test to compare the capillaroscopic findings and pulmonary function test. Values of p
ISSN:0003-4967
1468-2060
DOI:10.1136/annrheumdis-2012-eular.807