SAT0183 High Prevalence of Ultrasonographic Enthesopathy in Patients with Inflammatory Bowel Disease without Clinical Signs or Symptoms of Spondyloarthritis
Background 10-62% of Inflammatory Bowel Disease (IBD) patients have musculoskeletal manifestations, characterized by the appearance of peripheral arthritis, axial disease and enthesitis, mainly. Ultrasonography is more sensitive than physical examination to detect enthesopathy, so it may be useful t...
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Veröffentlicht in: | Annals of the rheumatic diseases 2014-06, Vol.73 (Suppl 2), p.656 |
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Sprache: | eng |
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Zusammenfassung: | Background 10-62% of Inflammatory Bowel Disease (IBD) patients have musculoskeletal manifestations, characterized by the appearance of peripheral arthritis, axial disease and enthesitis, mainly. Ultrasonography is more sensitive than physical examination to detect enthesopathy, so it may be useful to identify subclinical entheseal involvement. Objectives To evaluate the presence of enthesitis with power Doppler ultrasonography (PDUS) in IBD patients without clinically evident musculoskeletal disease and to investigate its correlation with IBD variables. Methods Cross-sectional study that recruited prospectively IBD patients, without clinically overt musculoskeletal disease, attended by Gastroenterology during 2013. Gastroenterological, rheumatological and PDUS evaluation, blind to each other, were performed. Clinical assessment included demographics, comorbidities, IBD characteristics (activity, phenotype, evolution time and clinical subtype), work and sport activities and musculoskeletal clinical examination. PDUS evaluation consisted of the detection of grey scale (GS) enthesopathy and entheseal power Doppler (PD) signal in 12 enthesis (bilateral triceps, cuadriceps, proximal and distal patellar, Achilles and plantar fascia enthesis), scored according to the Madrid Ankylosing Spondylitis Enthesitis Index (MASEI), using a LOGIQ7 General Electric machine with a 12-MHz linear array transducer. Statistical analysis: continuous variables are expressed as mean ± SD or range and categorical variables as number of cases (%). The associations between PDUS and clinical variables were evaluated by the Student's t test and Mann-Whitney test for continuous variables and by the χ2 test for categorical ones. Pearson and Spearman correlations of PDUS with clinical and analytical variables were also analyzed. The intra-reader agreement for US was estimated in all the images obtained. Statistical significance was set at p |
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ISSN: | 0003-4967 1468-2060 |
DOI: | 10.1136/annrheumdis-2014-eular.3884 |