THU0028 Interstitial Lung Disease in Primary SjÖGren Syndrome: A Gessar Analisys

Background Interstitial lung disease (ILD) in primary Sjögren Syndrome (pSS) includes Non Specific Interstitial Pneumonia (NSIP), Usual Interstitial Pneumonia (UIP), Lymphocytic interstitial pneumonia (LIP) and Organized Pneumonia (OP), all related to poor outcome. The existing frequency of ILD is unknown in Argentina. Objectives To describe the frequency of ILD in pSS using the Argentinean Group of Study for Sjögren Syndrome (GESSAR) database and to identify the associated features of the disease. Methods GESSAR database included 374 patients who fulfilled the 2002 criteria for pSS. The diagnosis of ILD was based on High Resolution Chest Computed Tomography (CT) according to the American-European Consensus for ILD. A control/case analysis was performed including patients with (cases) and without ILD (controls) with a 4:1 ratio. Mann-Whitney was employed for numeric variables and chi square or fisher's test for categorical variables. A p