AB0247 Rheumatoid arthritis patient characteristics at different therapeutic timepoints

Background Rheumatoid arthritis (RA) is a chronic inflammatory disease whose pathogenesis and response to therapy may differ at different therapeutic time points. While an immune-mediated inflammation may drive early disease, at late stages, a stromal reaction may prevail. Consequently tailored therapy within any phase of the disease requires better appreciation of both clinical, imaging and histopathological phenotypes. Objectives This study aims to investigate if there are any significant differences in these features at three distinct RA therapeutic timepoints. Methods Data was collected from 54 RA patients from 3 time points i)early RA (EAC), n=20, onset