FRI0397 Baseline characteristics of systemic sclerosis patients with borderline mean pulmonary artery pressure: post-hoc analysis from the detect study

Background Patients with mean pulmonary artery pressures (mPAP) of 21–24 mmHg have ‘borderline’ pulmonary arterial hypertension (PAH) and may represent an early, milder stage of pulmonary vasculopathy in those at high risk of PAH.1 Case detection strategies would facilitate investigation of natural...

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Veröffentlicht in:Annals of the rheumatic diseases 2013-06, Vol.72 (Suppl 3), p.A507-A508
Hauptverfasser: Khanna, D., Distler, O., Coghlan, J. G., Denton, C. P., Grünig, E., Bonderman, D., Müller-Ladner, U., Pope, J. E., Vonk, M. C., Torres-Martin, J.-V., Doelberg, M., Chadha-Boreham, H., Heinzl, H., Rosenberg, D. M., McLaughlin, V. V., Seibold, J. R.
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Sprache:eng
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Zusammenfassung:Background Patients with mean pulmonary artery pressures (mPAP) of 21–24 mmHg have ‘borderline’ pulmonary arterial hypertension (PAH) and may represent an early, milder stage of pulmonary vasculopathy in those at high risk of PAH.1 Case detection strategies would facilitate investigation of natural history and the value of intervention. Objectives Post-hoc analysis of systemic sclerosis (SSc) patients from the DETECT study to examine baseline characteristics of those with normal mPAP, borderline PAH (boPAP), and PAH. Methods DETECT was a multicentre cross-sectional study conducted to develop an evidence-based tool for detecting PAH in SSc patients to limit missed PAH diagnoses. Adults with SSc for >3 years, a DLCO
ISSN:0003-4967
1468-2060
DOI:10.1136/annrheumdis-2013-eular.1524