Targeting siglec-E on murine dendritic cells inhibits antigen presentation and CD4 and CD8 t cell responses

Targeting siglec-E on murine dendritic cells inhibits antigen presentation and CD4 and CD8 t cell responses

Siglecs are sialic acid-recognising lectins expressed on the cell surface of immune cells that regulate cellular adhesion, antigen uptake and signalling.

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Bibliographische Detailangaben
Veröffentlicht in:Annals of the rheumatic diseases 2010-03, Vol.69 (Suppl 2), p.A42-A42
Hauptverfasser: Bax, M, Unger, W, Kaur Singh, S, McKenzie, E J, Litjens, M, Garcia-Vallejo, J J, Saeland, E, van Vliet, S J, Crocker, P R, van Kooyk, Y
Format: Artikel
Sprache:eng
Schlagworte:
Antigen presentation
Dendritic cells
Lymphocytes
T cell receptors
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Beschreibung
Zusammenfassung:Siglecs are sialic acid-recognising lectins expressed on the cell surface of immune cells that regulate cellular adhesion, antigen uptake and signalling.
ISSN:0003-4967
1468-2060
DOI:10.1136/ard.2010.129627s