P001. ASSOCIATION OF CHRONIC OLIGOARTHRITIS WITH HLA CLASS II ALLELES: DRB1, DQB1 AND DQA1 IN BULGARIAN CHILDREN

Conclusion: Our data confirm predisposing JCA associations found in other Caucasian populations. Since the same HLA class II association was found in children with and without eye uveitis, patients without eye involvement are not safeguarded against development of uveitis. The aim of this study was to analyze the effects of ASCT at the site of inflammation. [...]we examined the changes in the cellular infiltrate and the expression of pro-inflammatory cytokines in the synovium in relation to clinical effects of ASCT. In vitro data suggest direct effects of glucocorticoids on growth plate chondrocytes. Since growth is the result of cell proliferation and -differentiation, the aim of the present study was to investigate the effects of dexamethason on these pathways crucial for normal growth plate function.