Thiazolidinediones for type 2 diabetes

Thiazolidinediones for type 2 diabetes

At Takeda Pharmaceuticals we have completed a clinical study (data on file, Takeda Europe, Research and Development Centre) in which we investigated the 6β-hydroxycortisol:free cortisol urinary ratio, commonly used as a specific marker of CYP3A4 induction. 3 Six healthy subjects received pioglitazo...

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Veröffentlicht in:BMJ 2001-01, Vol.322 (7280), p.235-236
Hauptverfasser: Glazer, N. Bradly, Cheatham, Wayman Wendell, Benbow, Alastair, Stewart, Murray, Yeoman, Guy
Format: Artikel
Sprache:eng
Schlagworte:
Cytochrome
Diabetes
Excretion
Heart failure
Letters
Metabolism
Pharmaceutical preparations
Protein isoforms
Steroids
Thiazolidinediones
Type 2 diabetes mellitus
Urine
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Beschreibung
Zusammenfassung:At Takeda Pharmaceuticals we have completed a clinical study (data on file, Takeda Europe, Research and Development Centre) in which we investigated the 6β-hydroxycortisol:free cortisol urinary ratio, commonly used as a specific marker of CYP3A4 induction. 3 Six healthy subjects received pioglitazone 45 mg once daily on day 1 and from day 3 to day 12.
ISSN:0959-8138
1468-5833
1756-1833
DOI:10.1136/bmj.322.7280.235