Advances and Applications in Organocatalytic Asymmetric aza-Michael Addition

Go forth and make bonds: The aza‐Michael addition is an excellent way of forming CN bonds and is of tremendous significance in asymmetric synthesis. Recently, impressive progress has been achieved by employing new nitrogen nucleophiles, suitable acceptors, and more efficient catalyst systems for this important transformation. This review surveys the advances among intermolecular‐ and intramolecular aza‐Michael addition and domino reactions involved aza‐Michael addition developed between 2010 and early 2012.