Cu(OTf)2 Catalyzed Synthesis of Bis(5-methyl-2-furyl)methanes by Condensation of 2-Methylfuran with Carbonyl Compounds under Solvent Free Conditions

A facile and efficient one‐pot three‐component synthesis of bis(5‐methyl‐2‐furyl)methanes has been achieved via the reaction of 2‐methylfuran with a series of aliphatic and aromatic aldehydes and aliphatic ketones in presence of copper(II) triflate under solvent free conditions. The bis(5‐methyl‐2‐furyl)methanes were obtained in 34% –72% yields and the catalyst was recycled up to four successive cycles without much loss in catalytic activity. A facile and efficient one‐pot three‐component synthesis of bis(5‐methyl‐2‐furyl)‐ methanes has been achieved, via the reaction of 2‐methylfuran with a series of aliphatic and aromatic aldehydes and aliphatic ketones in presence of copper(II) triflate under solvent free conditions. The bis(5‐methyl‐2‐furyl)methanes were obtained in 34% –72% yields and the catalyst was recycled up to four successive cycles without much loss in catalytic activity.