Heterogeneous versus Homogeneous Palladium Catalysts for Cross-Coupling Reactions

A large number of immobilized‐Pd‐catalysts for cross‐coupling reactions have been introduced in the last decade. Are the observed catalyzed reactions truly heterogeneous or are they homogeneous due to leached palladium? This account critically addresses the leaching issue by selectively referring to some of the newly developed catalytic systems in an attempt to evaluate said systems based on uniform criteria. The report is concluded by identifying the relevant chemical and structural challenges in the field. Solid as a palladium rock: Numerous immobilized‐Pd‐catalysts for crosscoupling reactions have been introduced in the last decade. Are the observed catalyzed reactions truly heterogeneous or are they homogeneous due to leached palladium? This account critically addresses the leaching issue by referring to some of the newly developed catalytic systems, aiming to evaluate them based on uniform criteria.