Membrane curvature bends the laws of physics and chemistry
A 'chemical biology of cellular membranes' must capture the way that mesoscale perturbations tune the biochemical properties of constituent lipid and protein molecules and vice versa. Whereas the classical paradigm focuses on chemical composition, dynamic modulation of the physical shape o...
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| Veröffentlicht in: | Nature chemical biology 2015-11, Vol.11 (11), p.822-825 |
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| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
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| Online-Zugang: | Volltext |
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| Zusammenfassung: | A 'chemical biology of cellular membranes' must capture the way that mesoscale perturbations tune the biochemical properties of constituent lipid and protein molecules and vice versa. Whereas the classical paradigm focuses on chemical composition, dynamic modulation of the physical shape or curvature of a membrane is emerging as a complementary and synergistic
modus operandi
for regulating cellular membrane biology. |
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| ISSN: | 1552-4450 1552-4469 |
| DOI: | 10.1038/nchembio.1941 |