Proton Pump Inhibitors (PPIs) May Modulate More Than Just Reflux in Chronic Rhinosinusitis with Nasal Polyps

In vitro, 5 different PPIs and the competitive H+/K+-ATPase inhibitor SCH-28080 all significantly inhibited IL-13-induced eotaxin-3 release by airway epithelial cells.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of allergy and clinical immunology 2016-02, Vol.137 (2), p.AB285-AB285
Hauptverfasser: Min, Jin Young, MD, PhD, Kern, Robert C., MD, Ocampo, Christopher J., MD, PhD, Stevens, Whitney W., MD, PhD, Price, Caroline P.E, Thompson, Christopher F., MD, Homma, Tetsuya, MD, PhD, Conley, David B., MD, Shintani-Smith, Stephanie, MD, Huang, Julia H, Suh, Lydia, BSc, Norton, James E., MS, Hulse, Kathryn E., PhD, Kato, Atsushi, PhD, Schleimer, Robert P., PhD, Tan, Bruce K., MD
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page AB285
container_issue 2
container_start_page AB285
container_title Journal of allergy and clinical immunology
container_volume 137
creator Min, Jin Young, MD, PhD
Kern, Robert C., MD
Ocampo, Christopher J., MD, PhD
Stevens, Whitney W., MD, PhD
Price, Caroline P.E
Thompson, Christopher F., MD
Homma, Tetsuya, MD, PhD
Conley, David B., MD
Shintani-Smith, Stephanie, MD
Huang, Julia H
Suh, Lydia, BSc
Norton, James E., MS
Hulse, Kathryn E., PhD
Kato, Atsushi, PhD
Schleimer, Robert P., PhD
Tan, Bruce K., MD
description In vitro, 5 different PPIs and the competitive H+/K+-ATPase inhibitor SCH-28080 all significantly inhibited IL-13-induced eotaxin-3 release by airway epithelial cells.
doi_str_mv 10.1016/j.jaci.2015.12.1179
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_1765339175</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0091674915029371</els_id><sourcerecordid>3953787351</sourcerecordid><originalsourceid>FETCH-LOGICAL-c2269-29dce4470a7428e61775495127f936260f28a446e8110a7bb9e480abef9b7f863</originalsourceid><addsrcrecordid>eNqFkU1v1DAQhi1EJZaWX8DFEhc4JHicxI4PIKEVlEUtRKWcLcc7URxSe7GT0v33JFokpF44zYz0vvPxDCEvgeXAQLwd8sFYl3MGVQ48B5DqCdkAUzITNa-ekg1jCjIhS_WMPE9pYEtd1GpDxiaGKXjazHcHuvO9a90UYqKvm2aX3tBrc6TXYT-PZsIliUhve-PplzlN9Aa7cX6gztNtH4N3lt70zofk_Jzc5BL97aaefjXJjLQJ4_GQLshZZ8aEL_7Gc_Lj08fb7efs6tvlbvvhKrOcC5VxtbdYlpIZWfIaBUhZlaoCLjtVCC5Yx2tTlgJrgEXTtgrLmpkWO9XKrhbFOXl16nuI4deMadJDmKNfRmqQoioKBbJaVMVJZWNIKWKnD9HdmXjUwPSKVQ96xapXrBq4XrEurncnFy4H3DuMOlmH3uLeRbST3gf3H__7R347ugWeGX_iEdO_RXXimunv6-PWv0HFuCokFH8AzsCUkw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1765339175</pqid></control><display><type>article</type><title>Proton Pump Inhibitors (PPIs) May Modulate More Than Just Reflux in Chronic Rhinosinusitis with Nasal Polyps</title><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>ScienceDirect Journals (5 years ago - present)</source><creator>Min, Jin Young, MD, PhD ; Kern, Robert C., MD ; Ocampo, Christopher J., MD, PhD ; Stevens, Whitney W., MD, PhD ; Price, Caroline P.E ; Thompson, Christopher F., MD ; Homma, Tetsuya, MD, PhD ; Conley, David B., MD ; Shintani-Smith, Stephanie, MD ; Huang, Julia H ; Suh, Lydia, BSc ; Norton, James E., MS ; Hulse, Kathryn E., PhD ; Kato, Atsushi, PhD ; Schleimer, Robert P., PhD ; Tan, Bruce K., MD</creator><creatorcontrib>Min, Jin Young, MD, PhD ; Kern, Robert C., MD ; Ocampo, Christopher J., MD, PhD ; Stevens, Whitney W., MD, PhD ; Price, Caroline P.E ; Thompson, Christopher F., MD ; Homma, Tetsuya, MD, PhD ; Conley, David B., MD ; Shintani-Smith, Stephanie, MD ; Huang, Julia H ; Suh, Lydia, BSc ; Norton, James E., MS ; Hulse, Kathryn E., PhD ; Kato, Atsushi, PhD ; Schleimer, Robert P., PhD ; Tan, Bruce K., MD</creatorcontrib><description>In vitro, 5 different PPIs and the competitive H+/K+-ATPase inhibitor SCH-28080 all significantly inhibited IL-13-induced eotaxin-3 release by airway epithelial cells.</description><identifier>ISSN: 0091-6749</identifier><identifier>EISSN: 1097-6825</identifier><identifier>DOI: 10.1016/j.jaci.2015.12.1179</identifier><language>eng</language><publisher>St. Louis: Elsevier Inc</publisher><subject>Allergy and Immunology ; Biomarkers</subject><ispartof>Journal of allergy and clinical immunology, 2016-02, Vol.137 (2), p.AB285-AB285</ispartof><rights>2016</rights><rights>Copyright Elsevier Limited Feb 2016</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jaci.2015.12.1179$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3548,27923,27924,45994</link.rule.ids></links><search><creatorcontrib>Min, Jin Young, MD, PhD</creatorcontrib><creatorcontrib>Kern, Robert C., MD</creatorcontrib><creatorcontrib>Ocampo, Christopher J., MD, PhD</creatorcontrib><creatorcontrib>Stevens, Whitney W., MD, PhD</creatorcontrib><creatorcontrib>Price, Caroline P.E</creatorcontrib><creatorcontrib>Thompson, Christopher F., MD</creatorcontrib><creatorcontrib>Homma, Tetsuya, MD, PhD</creatorcontrib><creatorcontrib>Conley, David B., MD</creatorcontrib><creatorcontrib>Shintani-Smith, Stephanie, MD</creatorcontrib><creatorcontrib>Huang, Julia H</creatorcontrib><creatorcontrib>Suh, Lydia, BSc</creatorcontrib><creatorcontrib>Norton, James E., MS</creatorcontrib><creatorcontrib>Hulse, Kathryn E., PhD</creatorcontrib><creatorcontrib>Kato, Atsushi, PhD</creatorcontrib><creatorcontrib>Schleimer, Robert P., PhD</creatorcontrib><creatorcontrib>Tan, Bruce K., MD</creatorcontrib><title>Proton Pump Inhibitors (PPIs) May Modulate More Than Just Reflux in Chronic Rhinosinusitis with Nasal Polyps</title><title>Journal of allergy and clinical immunology</title><description>In vitro, 5 different PPIs and the competitive H+/K+-ATPase inhibitor SCH-28080 all significantly inhibited IL-13-induced eotaxin-3 release by airway epithelial cells.</description><subject>Allergy and Immunology</subject><subject>Biomarkers</subject><issn>0091-6749</issn><issn>1097-6825</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNqFkU1v1DAQhi1EJZaWX8DFEhc4JHicxI4PIKEVlEUtRKWcLcc7URxSe7GT0v33JFokpF44zYz0vvPxDCEvgeXAQLwd8sFYl3MGVQ48B5DqCdkAUzITNa-ekg1jCjIhS_WMPE9pYEtd1GpDxiaGKXjazHcHuvO9a90UYqKvm2aX3tBrc6TXYT-PZsIliUhve-PplzlN9Aa7cX6gztNtH4N3lt70zofk_Jzc5BL97aaefjXJjLQJ4_GQLshZZ8aEL_7Gc_Lj08fb7efs6tvlbvvhKrOcC5VxtbdYlpIZWfIaBUhZlaoCLjtVCC5Yx2tTlgJrgEXTtgrLmpkWO9XKrhbFOXl16nuI4deMadJDmKNfRmqQoioKBbJaVMVJZWNIKWKnD9HdmXjUwPSKVQ96xapXrBq4XrEurncnFy4H3DuMOlmH3uLeRbST3gf3H__7R347ugWeGX_iEdO_RXXimunv6-PWv0HFuCokFH8AzsCUkw</recordid><startdate>20160201</startdate><enddate>20160201</enddate><creator>Min, Jin Young, MD, PhD</creator><creator>Kern, Robert C., MD</creator><creator>Ocampo, Christopher J., MD, PhD</creator><creator>Stevens, Whitney W., MD, PhD</creator><creator>Price, Caroline P.E</creator><creator>Thompson, Christopher F., MD</creator><creator>Homma, Tetsuya, MD, PhD</creator><creator>Conley, David B., MD</creator><creator>Shintani-Smith, Stephanie, MD</creator><creator>Huang, Julia H</creator><creator>Suh, Lydia, BSc</creator><creator>Norton, James E., MS</creator><creator>Hulse, Kathryn E., PhD</creator><creator>Kato, Atsushi, PhD</creator><creator>Schleimer, Robert P., PhD</creator><creator>Tan, Bruce K., MD</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7SS</scope><scope>7T5</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope></search><sort><creationdate>20160201</creationdate><title>Proton Pump Inhibitors (PPIs) May Modulate More Than Just Reflux in Chronic Rhinosinusitis with Nasal Polyps</title><author>Min, Jin Young, MD, PhD ; Kern, Robert C., MD ; Ocampo, Christopher J., MD, PhD ; Stevens, Whitney W., MD, PhD ; Price, Caroline P.E ; Thompson, Christopher F., MD ; Homma, Tetsuya, MD, PhD ; Conley, David B., MD ; Shintani-Smith, Stephanie, MD ; Huang, Julia H ; Suh, Lydia, BSc ; Norton, James E., MS ; Hulse, Kathryn E., PhD ; Kato, Atsushi, PhD ; Schleimer, Robert P., PhD ; Tan, Bruce K., MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2269-29dce4470a7428e61775495127f936260f28a446e8110a7bb9e480abef9b7f863</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Allergy and Immunology</topic><topic>Biomarkers</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Min, Jin Young, MD, PhD</creatorcontrib><creatorcontrib>Kern, Robert C., MD</creatorcontrib><creatorcontrib>Ocampo, Christopher J., MD, PhD</creatorcontrib><creatorcontrib>Stevens, Whitney W., MD, PhD</creatorcontrib><creatorcontrib>Price, Caroline P.E</creatorcontrib><creatorcontrib>Thompson, Christopher F., MD</creatorcontrib><creatorcontrib>Homma, Tetsuya, MD, PhD</creatorcontrib><creatorcontrib>Conley, David B., MD</creatorcontrib><creatorcontrib>Shintani-Smith, Stephanie, MD</creatorcontrib><creatorcontrib>Huang, Julia H</creatorcontrib><creatorcontrib>Suh, Lydia, BSc</creatorcontrib><creatorcontrib>Norton, James E., MS</creatorcontrib><creatorcontrib>Hulse, Kathryn E., PhD</creatorcontrib><creatorcontrib>Kato, Atsushi, PhD</creatorcontrib><creatorcontrib>Schleimer, Robert P., PhD</creatorcontrib><creatorcontrib>Tan, Bruce K., MD</creatorcontrib><collection>CrossRef</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Premium</collection><jtitle>Journal of allergy and clinical immunology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Min, Jin Young, MD, PhD</au><au>Kern, Robert C., MD</au><au>Ocampo, Christopher J., MD, PhD</au><au>Stevens, Whitney W., MD, PhD</au><au>Price, Caroline P.E</au><au>Thompson, Christopher F., MD</au><au>Homma, Tetsuya, MD, PhD</au><au>Conley, David B., MD</au><au>Shintani-Smith, Stephanie, MD</au><au>Huang, Julia H</au><au>Suh, Lydia, BSc</au><au>Norton, James E., MS</au><au>Hulse, Kathryn E., PhD</au><au>Kato, Atsushi, PhD</au><au>Schleimer, Robert P., PhD</au><au>Tan, Bruce K., MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Proton Pump Inhibitors (PPIs) May Modulate More Than Just Reflux in Chronic Rhinosinusitis with Nasal Polyps</atitle><jtitle>Journal of allergy and clinical immunology</jtitle><date>2016-02-01</date><risdate>2016</risdate><volume>137</volume><issue>2</issue><spage>AB285</spage><epage>AB285</epage><pages>AB285-AB285</pages><issn>0091-6749</issn><eissn>1097-6825</eissn><abstract>In vitro, 5 different PPIs and the competitive H+/K+-ATPase inhibitor SCH-28080 all significantly inhibited IL-13-induced eotaxin-3 release by airway epithelial cells.</abstract><cop>St. Louis</cop><pub>Elsevier Inc</pub><doi>10.1016/j.jaci.2015.12.1179</doi><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0091-6749
ispartof Journal of allergy and clinical immunology, 2016-02, Vol.137 (2), p.AB285-AB285
issn 0091-6749
1097-6825
language eng
recordid cdi_proquest_journals_1765339175
source Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; ScienceDirect Journals (5 years ago - present)
subjects Allergy and Immunology
Biomarkers
title Proton Pump Inhibitors (PPIs) May Modulate More Than Just Reflux in Chronic Rhinosinusitis with Nasal Polyps
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-11T21%3A38%3A47IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Proton%20Pump%20Inhibitors%20(PPIs)%20May%20Modulate%20More%20Than%20Just%20Reflux%20in%20Chronic%20Rhinosinusitis%20with%20Nasal%20Polyps&rft.jtitle=Journal%20of%20allergy%20and%20clinical%20immunology&rft.au=Min,%20Jin%20Young,%20MD,%20PhD&rft.date=2016-02-01&rft.volume=137&rft.issue=2&rft.spage=AB285&rft.epage=AB285&rft.pages=AB285-AB285&rft.issn=0091-6749&rft.eissn=1097-6825&rft_id=info:doi/10.1016/j.jaci.2015.12.1179&rft_dat=%3Cproquest_cross%3E3953787351%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1765339175&rft_id=info:pmid/&rft_els_id=S0091674915029371&rfr_iscdi=true