SIRT1 Attenuates Nasal Polypogenesis By Suppressing Epithelial-to-Mesenchymal Transition
SIRT1, a histone deacetylase, reportedly suppresses the transcriptional activity of HIF-1. [...]the authors hypothesized that SIRT1 attenuates nasal polyposis by inhibiting HIF-1-induced EMT.
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Veröffentlicht in: | Journal of allergy and clinical immunology 2016-02, Vol.137 (2), p.AB198-AB198 |
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container_issue | 2 |
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container_title | Journal of allergy and clinical immunology |
container_volume | 137 |
creator | Shin, Hyun-Woo Lee, Mingyu Kim, Dae Woo, MD |
description | SIRT1, a histone deacetylase, reportedly suppresses the transcriptional activity of HIF-1. [...]the authors hypothesized that SIRT1 attenuates nasal polyposis by inhibiting HIF-1-induced EMT. |
doi_str_mv | 10.1016/j.jaci.2015.12.776 |
format | Article |
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issn | 0091-6749 1097-6825 |
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source | Elsevier ScienceDirect Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
subjects | Allergy and Immunology Hypoxia Rodents |
title | SIRT1 Attenuates Nasal Polypogenesis By Suppressing Epithelial-to-Mesenchymal Transition |
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