Herpes Zoster Infection Prompting Diagnosis of Job's Syndrome in a Teenage Patient

Herpes Zoster Infection Prompting Diagnosis of Job's Syndrome in a Teenage Patient

Rationale Job's syndrome or autosomal dominant hyperimmunoglobulin E syndrome (AD-HIES) occurs due to defects in signal transducer and activator of transcription-3 (STAT3) and is characterized by staphylococcal abscesses, sinopulmonary infections, pneumatoceles, elevated IgE, candidiasis, bone...

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Veröffentlicht in:Journal of allergy and clinical immunology 2016-02, Vol.137 (2), p.AB223-AB223
Hauptverfasser: Bina, Sheila M., MD, Sriaroon, Panida, MD, Leiding, Jennifer W., MD
Format: Artikel
Sprache:eng
Schlagworte:
Allergy and Immunology
Defects
Ear diseases
Infections
Viral infections
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Zusammenfassung:Rationale Job's syndrome or autosomal dominant hyperimmunoglobulin E syndrome (AD-HIES) occurs due to defects in signal transducer and activator of transcription-3 (STAT3) and is characterized by staphylococcal abscesses, sinopulmonary infections, pneumatoceles, elevated IgE, candidiasis, bone fractures, delayed loss of primary teeth, and eczema.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2015.12.862