Fidarestat Decrease Allergic Sinus Congestion

Fidarestat Decrease Allergic Sinus Congestion

Conclusions These results indicate that FID can effectively reduce allergic sinus congestion by magnitudes similar to an anti-inflammatory steroid, in a human-relevant guinea pig model of allergic rhinitis. [...]we conclude that intranasal FID may be a desirable candidate for therapeutic development...

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Veröffentlicht in:Journal of allergy and clinical immunology 2016-02, Vol.137 (2), p.AB67-AB67
Hauptverfasser: Spear, Walter C., MSc, Belanger, KarryAnne K., BSc, Miller, Spotswood, BSc, Patrikeev, Igor, PhD, Motamedi, Massoud, PhD, Ramana, Kota V., PhD, Srivastava, Satish, PhD, Ameredes, Bill T., PhD
Format: Artikel
Sprache:eng
Schlagworte:
Allergies
Allergy and Immunology
Inflammation
Sinuses
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Zusammenfassung:Conclusions These results indicate that FID can effectively reduce allergic sinus congestion by magnitudes similar to an anti-inflammatory steroid, in a human-relevant guinea pig model of allergic rhinitis. [...]we conclude that intranasal FID may be a desirable candidate for therapeutic development in the treatment of allergic sinus inflammation and congestion.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2015.12.227