High Intraindividual Variation of N-Terminal Pro-Type Natriuretic Peptide in Urine of Patients with Stable Chronic Heart Failure: Comparison with Plasma

Metaanalyses have revealed that natriuretic peptide-guided therapy is superior to symptom-guided therapy in groups of patients with chronic heart failure (HF)1 (1). Author Contributions: All authors confirmed they have contributed to the intellectual content of this paper and have met the following 3 requirements: (a) significant contributions to the conception and design, acquisition of data, or analysis and interpretation of data; (b) drafting or revising the article for intellectual content; and (c) final approval of the published article.