Statin Initiation During Childhood in Patients With Familial Hypercholesterolemia

Statin Initiation During Childhood in Patients With Familial Hypercholesterolemia

To prevent premature CVD in adult life, guidelines advocate initiation of statins in childhood (2). Furthermore, earlier initiation of statin therapy was associated with thinner carotid IMT at follow-up. Because carotid IMT is an established marker of early atherosclerosis, these results support the...

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Veröffentlicht in:Journal of the American College of Cardiology 2016-02, Vol.67 (4), p.455-456
Hauptverfasser: Braamskamp, Marjet J.A.M., MD, PhD, Kastelein, John J.P., MD, PhD, Kusters, D. Meeike, MD, Hutten, Barbara A., MD, PhD, Wiegman, Albert, MD, PhD
Format: Artikel
Sprache:eng
Schlagworte:
Cardiology
Cardiovascular
Cholesterol
Heart attacks
Internal Medicine
Statins
Young adults
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Zusammenfassung:To prevent premature CVD in adult life, guidelines advocate initiation of statins in childhood (2). Furthermore, earlier initiation of statin therapy was associated with thinner carotid IMT at follow-up. Because carotid IMT is an established marker of early atherosclerosis, these results support the pivotal role of statins in the inhibition of the development of early atherosclerotic lesions in FH children.
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2015.11.021