ChemInform Abstract: Enantioselective Palladium(0)-Catalyzed Intramolecular Cyclopropane Functionalization: Access to Dihydroquinolones, Dihydroisoquinolones and the BMS-791325 Ring System

The utility of this method is demonstrated in the enantioselective synthesis of compound (XIX), representing the core structure of hepatitis C virus NS5B replicase inhibitor BMS‐791325.

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Bibliographische Detailangaben
Veröffentlicht in:	ChemInform 2015-12, Vol.47 (1), p.no-no
Hauptverfasser:	Pedroni, J., Saget, T., Donets, P. A., Cramer, N.
Format:	Artikel
Sprache:	eng
Schlagworte:	annulation reactions catalysis catalysis, phase‐transfer catalysis diastereoselective syntheses diastereoselective syntheses, enantioselective syntheses (incl. cis/trans‐isomerism) enantioselective syntheses (incl. cis/trans-isomerism) fused pyridine derivatives isoquinoline derivatives phase-transfer catalysis quinoline derivatives ring closure reactions ring closure reactions, annulation reactions
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Beschreibung
Zusammenfassung:	The utility of this method is demonstrated in the enantioselective synthesis of compound (XIX), representing the core structure of hepatitis C virus NS5B replicase inhibitor BMS‐791325.
ISSN:	0931-7597 1522-2667
DOI:	10.1002/chin.201601034