In-Vitro and in-Vivo Anti-Inflammatory Activities of Salvia hispanica and Linum usitatissium Seeds in Swiss Albino Rats

Salvia hispanica called as Chia seeds family Lamiaceae and Linum usitatissium called as Flax seeds family Linaceae was evaluated for its invitro and invivo anti-anti inflammatory activities individually and combined in swiss albio rats. Phytochemical screening analysis of both seeds revealed the presence of flavanoids. The Fourier Transform Infrared Spectrophotometer (FTIR) analysis of chia and flax seeds confirmed the presence of amide, alcohols, phenols, alkanes, carboxylic acids, aldehydes, ketones, alkenes, primary amines, aromatics, esters, ethers, alkyl halides and aliphatic amines compounds, which showed major peaks. In-vivo anti-inflammatory activity was done on Swiss albino rats (150–250 gms) at two different doses (100 and 200 mg/kg body weight) by using 1% histamine induced paw edema test. In-vitro anti-inflammatory test was done by proteindenaturation and the human red blood cell (HRBC) membrane stabilization method. Data were analyzed by oneway analysis of variance (ANOVA) followed by Dunnett's t-test and the test of significance P value