ChemInform Abstract: Asymmetric Transfer Hydrogenation of [alpha]-Amino [beta]-Keto Ester Hydrochlorides Through Dynamic Kinetic Resolution

The asymmetric transfer hydrogenation of [alpha]-amino [beta]-keto ester hydrochlorides is reported for the first time using a ruthenium catalyst in combination with ammonium formate as the hydrogen source.

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Veröffentlicht in:ChemInform 2015-11, Vol.46 (46)
Hauptverfasser: Echeverria, Pierre-Georges, Cornil, Johan, Ferard, Charlene, Guerinot, Amandine, Cossy, Janine, Phansavath, Phannarath, Ratovelomanana-Vidal, Virginie
Format: Artikel
Sprache:eng
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Zusammenfassung:The asymmetric transfer hydrogenation of [alpha]-amino [beta]-keto ester hydrochlorides is reported for the first time using a ruthenium catalyst in combination with ammonium formate as the hydrogen source.
ISSN:0931-7597
1522-2667
DOI:10.1002/chin.201546082