Depression in Chinese patients with type 2 diabetes: associations with hyperglycemia, hypoglycemia, and poor treatment adherence; 2éæ...ä½Zä¾oe

Background We hypothesize that depression in type 2 diabetes might be associated with poor glycemic control, in part due to suboptimal self-care. We tested this hypothesis by examining the associations of depression with clinical and laboratory findings in a multicenter survey of Chinese type 2 diabetic patients. Method 2538 patients aged 18-75 years attending hospital-based clinics in four cities in China underwent detailed clinical-psychological-behavioral assessment during a 12-month period between 2011 and 2012. Depression was diagnosed if Patient Health Questionnaire-9 (PHQ-9) score ≥10. Diabetes self-care and medication adherence were assessed using the Summary of Diabetes Self-care Activities and the 4-item Morisky medication adherence scale respectively. Results In this cross-sectional study (mean age: 56.4±10.5[SD] years, 53% men), 6.1% (n=155) had depression. After controlling for study sites, patients with depression had higher HbA1c (7.9±2.0 vs. 7.7±2.0%, P=0.008) and were less likely to achieve HbA1c goal of