GW26-e0208 Naturally occurring multiple-modified low density lipoprotein (LDL)

After 48-72 hours, loss of Î±-tocopherol, increase of susceptibility to oxidation, and accumulation of lipid peroxidation products in LDL are observed. [...]multiple modification of LDL is a cascade of sequential changes in lipoprotein particle, namely: desialylation, loss of lipids, size reduction,...

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Veröffentlicht in:	Journal of the American College of Cardiology 2015-10, Vol.66 (16), p.C71-C71
Hauptverfasser:	Orekhov, Alexander N, Elizova, Natalia V, Melnichenko, Alexandra A, Karagodin, Vasily P, Myasoedova, Veronika A, Zhelankin, Andrey V, Trubinov, Sergey S, Orekhova, Varvara A, Sinyov, Vasily V, Barinova, Valeria A, Ryzhkova, Anastasia V, Bobryshev, Yuri V, Sobenin, Igor A
Format:	Artikel
Sprache:	eng
Schlagworte:	Atherosclerosis Cardiology Cardiovascular Cholesterol Internal Medicine Lipid peroxidation Lipids Low density lipoprotein
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	After 48-72 hours, loss of Î±-tocopherol, increase of susceptibility to oxidation, and accumulation of lipid peroxidation products in LDL are observed. [...]multiple modification of LDL is a cascade of sequential changes in lipoprotein particle, namely: desialylation, loss of lipids, size reduction, increase of electronegative charge, lipid peroxidation in LDL.
ISSN:	0735-1097 1558-3597
DOI:	10.1016/j.jacc.2015.06.1298