GW26-e2401 Enhanced levels of miR-122-5p and let-7b-3p in aortas of spontaneously hypertensive rats associated with downregulated levels of Apelin, miR-1-3p, miR-376b-3p and miR-298-5p

GW26-e2401 Enhanced levels of miR-122-5p and let-7b-3p in aortas of spontaneously hypertensive rats associated with downregulated levels of Apelin, miR-1-3p, miR-376b-3p and miR-298-5p

[...]Apelin is an important negative regulator of the hypertension-induced pathological hypertrophy and aortic remodeling and attenuates aortic ultrastructural injury in hypertensive rats.

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Bibliographische Detailangaben
Veröffentlicht in:Journal of the American College of Cardiology 2015-10, Vol.66 (16), p.C77-C77
Hauptverfasser: Zhong, Jiuchang, Xu, Ran, Chen, Laijiang, Zhang, Zhenzhou, Xu, Yingle, Chang, Qing, Zhu, Dingliang, Gao, Pingjin
Format: Artikel
Sprache:eng
Schlagworte:
Cardiology
Cardiovascular
Coronary vessels
Hypertension
Internal Medicine
Rodents
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Beschreibung
Zusammenfassung:[...]Apelin is an important negative regulator of the hypertension-induced pathological hypertrophy and aortic remodeling and attenuates aortic ultrastructural injury in hypertensive rats.
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2015.06.307