GW26-e4353 Angiotensin II Induces Atrial Fibrillation Through STAT3 Mediated Atrial Structural Remodeling

GW26-e4353 Angiotensin II Induces Atrial Fibrillation Through STAT3 Mediated Atrial Structural Remodeling

Results In atrial myocytes, incubation with AngII increased level of apoptosis, expressions of caspase 3 and 8, release of cytochrome C from mitochondria to cytosol after OGD pretreatment, which was inhibited by losartan and WP1066.

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Veröffentlicht in:Journal of the American College of Cardiology 2015-10, Vol.66 (16), p.C27-C27
Hauptverfasser: Zheng, Liuying, Du, Xinping
Format: Artikel
Sprache:eng
Schlagworte:
Apoptosis
Cardiac arrhythmia
Cardiology
Cardiovascular
Cytochrome
Fibroblasts
Internal Medicine
Rodents
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Beschreibung
Zusammenfassung:Results In atrial myocytes, incubation with AngII increased level of apoptosis, expressions of caspase 3 and 8, release of cytochrome C from mitochondria to cytosol after OGD pretreatment, which was inhibited by losartan and WP1066.
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2015.06.1129