GW26-e1388 Transplantation of EPCs Overexpressing S1PR3 Promotes Vascular Repair in the Early Phase After Vascular Injury

Conclusions Our data suggest that transplantation of EPCs overexpressing S1PR3 can have a combined effect of both amplifying the reendothelialization capacity of EPCs and inhibiting neointima formation so as to facilitate better inhibition of adverse remodeling after vascular injury. [...]gene modif...

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Veröffentlicht in:Journal of the American College of Cardiology 2015-10, Vol.66 (16), p.C31-C31
Hauptverfasser: Wang, Hang, Cai, Keyin, Wang, Li, Zhao, Kehong, Tu, Ying, Wang, Xiao, Li, Jiahuan, Huang, Hao
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container_end_page C31
container_issue 16
container_start_page C31
container_title Journal of the American College of Cardiology
container_volume 66
creator Wang, Hang
Cai, Keyin
Wang, Li
Zhao, Kehong
Tu, Ying
Wang, Xiao
Li, Jiahuan
Huang, Hao
description Conclusions Our data suggest that transplantation of EPCs overexpressing S1PR3 can have a combined effect of both amplifying the reendothelialization capacity of EPCs and inhibiting neointima formation so as to facilitate better inhibition of adverse remodeling after vascular injury. [...]gene modified EPCs may be applied in clinical progenitor cell therapy to improve vascular repair after vascular injury.
doi_str_mv 10.1016/j.jacc.2015.06.1144
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subjects Angioplasty
Cardiology
Cardiovascular
Carotid arteries
Internal Medicine
Veins & arteries
title GW26-e1388 Transplantation of EPCs Overexpressing S1PR3 Promotes Vascular Repair in the Early Phase After Vascular Injury
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