ChemInform Abstract: Pd-Imidate Complexes as Recyclable Catalysts for the Synthesis of C5-Alkenylated Pyrimidine Nucleosides via Heck Cross-Coupling Reaction

ChemInform Abstract: Pd-Imidate Complexes as Recyclable Catalysts for the Synthesis of C5-Alkenylated Pyrimidine Nucleosides via Heck Cross-Coupling Reaction

The new approach is used for the highly efficient scale‐up synthesis of the HSV‐1 inhibitor Brivudine (BVDU) (IV).

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Veröffentlicht in:ChemInform 2015-08, Vol.46 (31), p.no-no
Hauptverfasser: Ardhapure, Ajaykumar V., Sanghvi, Yogesh S., Kapdi, Anant R., Garcia, Joaquin, Sanchez, Gregorio, Lozano, Pedro, Serrano, J. Luis
Format: Artikel
Sprache:eng
Schlagworte:
C-C bond formation
medicinal chemistry
nucleic acids
pharmacology
pharmacology, medicinal chemistry, vaccines, serums
serums
vaccines
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Beschreibung
Zusammenfassung:The new approach is used for the highly efficient scale‐up synthesis of the HSV‐1 inhibitor Brivudine (BVDU) (IV).
ISSN:0931-7597
1522-2667
DOI:10.1002/chin.201531240